Multiple virtual screening approaches for finding new Hepatitis c virus RNA-dependent RNA polymerase inhibitors: Structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors

Abstract The RNA polymerase NS5B of Hepatitis C virus (HCV) Ingredient Bins is a well-characterised drug target with an active site and four allosteric binding sites.This work presents a workflow for virtual screening and its application to Drug Bank screening targeting the Hepatitis C Virus (HCV) RNA polymerase non-nucleoside binding sites.Potenti

read more


Fabrication of a Transparent Anti-stain Thin Film Using an Atmospheric Pressure Cold Plasma Deposition System

Recently, outdoor-constructed solar panels have a problem such as power generation efficiency is reduced by the face plate dirt.On LADIES KNITWEAR URBAN CARDIGAN the other hand, electronic touch panels have a problem such as deterioration of visibility of the screen by finger grease stain.To solve these problems, we need to fabricate the anti-stain

read more


Development and validation of a scale to measure the quality of patient medication counseling using Rasch model

Objective: The purpose of this study is to develop and validate the psychometric properties of a scale for measuring the quality of patient medication counseling by using the Rasch model.Methods: In this study, the scale was developed based on the literature review.It consisted of 31 items across five subscales: introduction, problem identification

read more